BDBM50251116 CHEMBL465868::N-tert-Butyl-4-((4-chlorophenyl)(2-(trifluoromethyl)-phenyl)methyl)piperazine-1-carboxamide

SMILES: CC(C)(C)NC(=O)N1CCN(CC1)C(c1ccc(Cl)cc1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=DSQRJZAYFRQLGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50251116 (CHEMBL465868 | N-tert-Butyl-4-((4-chlorophenyl)(2-...) Show SMILES CC(C)(C)NC(=O)N1CCN(CC1)C(c1ccc(Cl)cc1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C23H27ClF3N3O/c1-22(2,3)28-21(31)30-14-12-29(13-15-30)20(16-8-10-17(24)11-9-16)18-6-4-5-7-19(18)23(25,26)27/h4-11,20H,12-15H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebella membrane				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair