BDBM50251153 CHEMBL4093649

SMILES: Cc1cc(Nc2nc(nc3ccc(Cl)cc23)C(=O)N2CCOCC2)n[nH]1

InChI Key: InChIKey=REZJPRGFFAPIPT-UHFFFAOYSA-N

Data: 1 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50251153 (CHEMBL4093649) Show SMILES Cc1cc(Nc2nc(nc3ccc(Cl)cc23)C(=O)N2CCOCC2)n[nH]1 Show InChI InChI=1S/C17H17ClN6O2/c1-10-8-14(23-22-10)20-15-12-9-11(18)2-3-13(12)19-16(21-15)17(25)24-4-6-26-7-5-24/h2-3,8-9H,4-7H2,1H3,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...				J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50251153 (CHEMBL4093649) Show SMILES Cc1cc(Nc2nc(nc3ccc(Cl)cc23)C(=O)N2CCOCC2)n[nH]1 Show InChI InChI=1S/C17H17ClN6O2/c1-10-8-14(23-22-10)20-15-12-9-11(18)2-3-13(12)19-16(21-15)17(25)24-4-6-26-7-5-24/h2-3,8-9H,4-7H2,1H3,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Binding affinity to biotin-labeled human truncated PAK4 kinase domain by surface plasmon resonance assay				J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN
					More data for this Ligand-Target Pair