BDBM50251154 CHEMBL4095155

SMILES: Cc1cc(Nc2nc(nc3ccc(Cl)cc23)C(=O)N2CCNC(=O)C2)n[nH]1

InChI Key: InChIKey=DCJXIFWOSUVWRA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50251154 (CHEMBL4095155) Show SMILES Cc1cc(Nc2nc(nc3ccc(Cl)cc23)C(=O)N2CCNC(=O)C2)n[nH]1 Show InChI InChI=1S/C17H16ClN7O2/c1-9-6-13(24-23-9)21-15-11-7-10(18)2-3-12(11)20-16(22-15)17(27)25-5-4-19-14(26)8-25/h2-3,6-7H,4-5,8H2,1H3,(H,19,26)(H2,20,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...				J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN
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