BDBM50251182 CHEMBL4069074

SMILES: Cc1cc(Nc2nc(nc3ccc(Cl)cc23)C(=O)N2CCC(N)CC2)n[nH]1

InChI Key: InChIKey=UTFKJYFRHSSYPD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50251182 (CHEMBL4069074) Show SMILES Cc1cc(Nc2nc(nc3ccc(Cl)cc23)C(=O)N2CCC(N)CC2)n[nH]1 Show InChI InChI=1S/C18H20ClN7O/c1-10-8-15(25-24-10)22-16-13-9-11(19)2-3-14(13)21-17(23-16)18(27)26-6-4-12(20)5-7-26/h2-3,8-9,12H,4-7,20H2,1H3,(H2,21,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	354	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...				J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN
					More data for this Ligand-Target Pair