BDBM50251303 CHEMBL4078189

SMILES: Cc1ccccc1-n1nc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(C)cc1=O

InChI Key: InChIKey=ZAUITWXGIQXSFV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50251303 (CHEMBL4078189) Show SMILES Cc1ccccc1-n1nc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(C)cc1=O Show InChI InChI=1S/C26H20FN5O3/c1-15-5-3-4-6-20(15)32-23(33)13-16(2)24(31-32)26(34)30-17-7-8-22(19(27)14-17)35-21-10-12-29-25-18(21)9-11-28-25/h3-14H,1-2H3,(H,28,29)(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China. Electronic address: tangqidongcn@126.com. Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Eur J Med Chem 133: 97-106 (2017) Article DOI: 10.1016/j.ejmech.2017.03.045 BindingDB Entry DOI: 10.7270/Q2K35X3B
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