null

SMILES: NS(=O)(=O)c1nnc(\N=C\c2cccc(\C=N\c3nnc(s3)S(N)(=O)=O)c2)s1

InChI Key: InChIKey=YIQRFEPXEHEUFQ-IAGONARPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50251369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50251369 (CHEMBL4084006) Show SMILES NS(=O)(=O)c1nnc(\N=C\c2cccc(\C=N\c3nnc(s3)S(N)(=O)=O)c2)s1 Show InChI InChI=1S/C12H10N8O4S4/c13-27(21,22)11-19-17-9(25-11)15-5-7-2-1-3-8(4-7)6-16-10-18-20-12(26-10)28(14,23)24/h1-6H,(H2,13,21,22)(H2,14,23,24)/b15-5+,16-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Adiyaman University, 02040 Adiyaman, Turkey. Electronic address: akocaksuleyman@gmail.com. Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 incubated for 10 mins by stopped flow CO2 hydrase assay				Bioorg Med Chem 25: 3093-3097 (2017) Article DOI: 10.1016/j.bmc.2017.03.063 BindingDB Entry DOI: 10.7270/Q25T3NXJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50251369 (CHEMBL4084006) Show SMILES NS(=O)(=O)c1nnc(\N=C\c2cccc(\C=N\c3nnc(s3)S(N)(=O)=O)c2)s1 Show InChI InChI=1S/C12H10N8O4S4/c13-27(21,22)11-19-17-9(25-11)15-5-7-2-1-3-8(4-7)6-16-10-18-20-12(26-10)28(14,23)24/h1-6H,(H2,13,21,22)(H2,14,23,24)/b15-5+,16-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Adiyaman University, 02040 Adiyaman, Turkey. Electronic address: akocaksuleyman@gmail.com. Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 incubated for 10 mins by stopped flow CO2 hydrase assay				Bioorg Med Chem 25: 3093-3097 (2017) Article DOI: 10.1016/j.bmc.2017.03.063 BindingDB Entry DOI: 10.7270/Q25T3NXJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50251369 (CHEMBL4084006) Show SMILES NS(=O)(=O)c1nnc(\N=C\c2cccc(\C=N\c3nnc(s3)S(N)(=O)=O)c2)s1 Show InChI InChI=1S/C12H10N8O4S4/c13-27(21,22)11-19-17-9(25-11)15-5-7-2-1-3-8(4-7)6-16-10-18-20-12(26-10)28(14,23)24/h1-6H,(H2,13,21,22)(H2,14,23,24)/b15-5+,16-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Adiyaman University, 02040 Adiyaman, Turkey. Electronic address: akocaksuleyman@gmail.com. Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 7 incubated for 10 mins by stopped flow CO2 hydrase assay				Bioorg Med Chem 25: 3093-3097 (2017) Article DOI: 10.1016/j.bmc.2017.03.063 BindingDB Entry DOI: 10.7270/Q25T3NXJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50251369 (CHEMBL4084006) Show SMILES NS(=O)(=O)c1nnc(\N=C\c2cccc(\C=N\c3nnc(s3)S(N)(=O)=O)c2)s1 Show InChI InChI=1S/C12H10N8O4S4/c13-27(21,22)11-19-17-9(25-11)15-5-7-2-1-3-8(4-7)6-16-10-18-20-12(26-10)28(14,23)24/h1-6H,(H2,13,21,22)(H2,14,23,24)/b15-5+,16-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Adiyaman University, 02040 Adiyaman, Turkey. Electronic address: akocaksuleyman@gmail.com. Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 incubated for 10 mins by stopped flow CO2 hydrase assay				Bioorg Med Chem 25: 3093-3097 (2017) Article DOI: 10.1016/j.bmc.2017.03.063 BindingDB Entry DOI: 10.7270/Q25T3NXJ
					More data for this Ligand-Target Pair