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SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)Nc1cc(ccc1CO)C(F)(F)F

InChI Key: InChIKey=QAVMYAXPFYKWRF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251405   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor 1


(Homo sapiens (Human))		BDBM50251405
PNG
((2-(2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetrah...)
Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)Nc1cc(ccc1CO)C(F)(F)F
Show InChI InChI=1S/C28H31F3N2O2/c1-4-17-8-6-9-18(5-2)26(17)24-15-25(35-3)27-21(10-7-11-22(27)33-24)32-23-14-20(28(29,30)31)13-12-19(23)16-34/h6,8-9,12-15,21,32,34H,4-5,7,10-11,16H2,1-3H3
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PC sid
UniChem

Similars
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 18: 3852-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.059
BindingDB Entry DOI: 10.7270/Q2765F4X
More data for this
Ligand-Target Pair