BDBM50251489 CHEMBL481089::butyl 5-isobutyl-3-(4-(isopropylcarbamoyl)phenyl)thiophen-2-ylsulfonylcarbamate

SMILES: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)NC(C)C

InChI Key: InChIKey=BBBLYZCYWLNHFC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50251489 (CHEMBL481089 | butyl 5-isobutyl-3-(4-(isopropylcar...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)NC(C)C Show InChI InChI=1S/C23H32N2O5S2/c1-6-7-12-30-23(27)25-32(28,29)22-20(14-19(31-22)13-15(2)3)17-8-10-18(11-9-17)21(26)24-16(4)5/h8-11,14-16H,6-7,12-13H2,1-5H3,(H,24,26)(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
AGTR1 (RAT)	BDBM50251489 (CHEMBL481089 | butyl 5-isobutyl-3-(4-(isopropylcar...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)NC(C)C Show InChI InChI=1S/C23H32N2O5S2/c1-6-7-12-30-23(27)25-32(28,29)22-20(14-19(31-22)13-15(2)3)17-8-10-18(11-9-17)21(26)24-16(4)5/h8-11,14-16H,6-7,12-13H2,1-5H3,(H,24,26)(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT1 receptor in rat liver membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair