BDBM50251536 CHEMBL517685::butyl 5-isobutyl-3-(4-(pyrrolidine-1-carbonyl)phenyl)thiophen-2-ylsulfonylcarbamate

SMILES: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)N1CCCC1

InChI Key: InChIKey=JAVKHUMSFXERNK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50251536 (CHEMBL517685 | butyl 5-isobutyl-3-(4-(pyrrolidine-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C24H32N2O5S2/c1-4-5-14-31-24(28)25-33(29,30)23-21(16-20(32-23)15-17(2)3)18-8-10-19(11-9-18)22(27)26-12-6-7-13-26/h8-11,16-17H,4-7,12-15H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
AGTR1 (RAT)	BDBM50251536 (CHEMBL517685 | butyl 5-isobutyl-3-(4-(pyrrolidine-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C24H32N2O5S2/c1-4-5-14-31-24(28)25-33(29,30)23-21(16-20(32-23)15-17(2)3)18-8-10-19(11-9-18)22(27)26-12-6-7-13-26/h8-11,16-17H,4-7,12-15H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT1 receptor in rat liver membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair