BDBM50251603 (+/-)-2-(2,6-diethylphenyl)-4-methoxy-N-(4-methoxy-2-methylphenyl)-N-methyl-5,6,7,8-tetrahydroquinolin-5-amine::CHEMBL479543

SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1ccc(OC)cc1C

InChI Key: InChIKey=JPGZXIYEXVGIKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50251603 ((+/-)-2-(2,6-diethylphenyl)-4-methoxy-N-(4-methoxy...) Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1ccc(OC)cc1C Show InChI InChI=1S/C29H36N2O2/c1-7-20-11-9-12-21(8-2)28(20)24-18-27(33-6)29-23(30-24)13-10-14-26(29)31(4)25-16-15-22(32-5)17-19(25)3/h9,11-12,15-18,26H,7-8,10,13-14H2,1-6H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 18: 3852-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.059 BindingDB Entry DOI: 10.7270/Q2765F4X
					More data for this Ligand-Target Pair