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BDBM50251616 CHEMBL521427::biphenyl-4-carboxylic acid methyl-[(3-nitro-4-thiomorpholin-4-yl-phenyl-carbamoyl)-methyl]-amide

SMILES: CN(CC(=O)Nc1ccc(N2CCSCC2)c(c1)[N+]([O-])=O)C(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=TUYNZLREPSCMCV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251616   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
BCL-W


(Homo sapiens (Human))		BDBM50251616
PNG
(CHEMBL521427 | biphenyl-4-carboxylic acid methyl-[...)
Show SMILES CN(CC(=O)Nc1ccc(N2CCSCC2)c(c1)[N+]([O-])=O)C(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C26H26N4O4S/c1-28(26(32)21-9-7-20(8-10-21)19-5-3-2-4-6-19)18-25(31)27-22-11-12-23(24(17-22)30(33)34)29-13-15-35-16-14-29/h2-12,17H,13-16,18H2,1H3,(H,27,31)
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KEGG

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PC sid
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Similars
Article
PubMed
 1.30E+4n/an/an/an/an/an/an/an/a



University of Pittsburgh

Curated by ChEMBL


Assay Description
Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assay

Bioorg Med Chem Lett 18: 4115-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.096
BindingDB Entry DOI: 10.7270/Q2DZ083N
More data for this
Ligand-Target Pair