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BDBM50251652 Biphenyl-4-carboxylic acid {[4-(adamantan-1-ylamino)-3-nitro-phenylcarbamoyl]-methyl}-methyl-amide::CHEMBL521253

SMILES: CN(CC(=O)Nc1ccc(NC23CC4CC(CC(C4)C2)C3)c(c1)[N+]([O-])=O)C(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=AOFRQEULWOEANT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251652   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
BCL-W


(Homo sapiens (Human))		BDBM50251652
PNG
(Biphenyl-4-carboxylic acid {[4-(adamantan-1-ylamin...)
Show SMILES CN(CC(=O)Nc1ccc(NC23CC4CC(CC(C4)C2)C3)c(c1)[N+]([O-])=O)C(=O)c1ccc(cc1)-c1ccccc1 |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11|
Show InChI InChI=1S/C32H34N4O4/c1-35(31(38)26-9-7-25(8-10-26)24-5-3-2-4-6-24)20-30(37)33-27-11-12-28(29(16-27)36(39)40)34-32-17-21-13-22(18-32)15-23(14-21)19-32/h2-12,16,21-23,34H,13-15,17-20H2,1H3,(H,33,37)
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 9.43E+3n/an/an/an/an/an/an/an/a



University of Pittsburgh

Curated by ChEMBL


Assay Description
Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assay

Bioorg Med Chem Lett 18: 4115-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.096
BindingDB Entry DOI: 10.7270/Q2DZ083N
More data for this
Ligand-Target Pair