null

SMILES: Clc1ccc2c(c1)[nH]c(=O)c1c3C(=O)C=CC(=O)c3ccc21

InChI Key: InChIKey=ZYDXDOJLAALCSU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
M-phase inducer phosphatase 3 (Homo sapiens (Human))	BDBM50251710 (CHEMBL4082819) Show SMILES Clc1ccc2c(c1)[nH]c(=O)c1c3C(=O)C=CC(=O)c3ccc21 |c:15| Show InChI InChI=1S/C17H8ClNO3/c18-8-1-2-9-10-3-4-11-13(20)5-6-14(21)15(11)16(10)17(22)19-12(9)7-8/h1-7H,(H,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged CDC25C expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as s...				Eur J Med Chem 134: 316-333 (2017) Article DOI: 10.1016/j.ejmech.2017.04.012 BindingDB Entry DOI: 10.7270/Q2WD4311
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 1 (Homo sapiens (Human))	BDBM50251710 (CHEMBL4082819) Show SMILES Clc1ccc2c(c1)[nH]c(=O)c1c3C(=O)C=CC(=O)c3ccc21 |c:15| Show InChI InChI=1S/C17H8ClNO3/c18-8-1-2-9-10-3-4-11-13(20)5-6-14(21)15(11)16(10)17(22)19-12(9)7-8/h1-7H,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-cytisine binding from high-affinity Nicotinic acetylcholine receptor in rat brain (principall...				Eur J Med Chem 134: 316-333 (2017) Article DOI: 10.1016/j.ejmech.2017.04.012 BindingDB Entry DOI: 10.7270/Q2WD4311
					More data for this Ligand-Target Pair