null

SMILES: O=C1C=CC(=O)c2c1ccc1c3ccccc3oc(=O)c21

InChI Key: InChIKey=HFHCEBAWIQEUHF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
M-phase inducer phosphatase 3 (Homo sapiens (Human))	BDBM50251722 (CHEMBL4098262) Show SMILES O=C1C=CC(=O)c2c1ccc1c3ccccc3oc(=O)c21 |c:2| Show InChI InChI=1S/C17H8O4/c18-12-7-8-13(19)15-11(12)6-5-10-9-3-1-2-4-14(9)21-17(20)16(10)15/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged CDC25C expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as s...				Eur J Med Chem 134: 316-333 (2017) Article DOI: 10.1016/j.ejmech.2017.04.012 BindingDB Entry DOI: 10.7270/Q2WD4311
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50251722 (CHEMBL4098262) Show SMILES O=C1C=CC(=O)c2c1ccc1c3ccccc3oc(=O)c21 |c:2| Show InChI InChI=1S/C17H8O4/c18-12-7-8-13(19)15-11(12)6-5-10-9-3-1-2-4-14(9)21-17(20)16(10)15/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged truncated CDC25B expressed in bacterial expression system using 3-O-methylfluorescein phosphate as substra...				Eur J Med Chem 134: 316-333 (2017) Article DOI: 10.1016/j.ejmech.2017.04.012 BindingDB Entry DOI: 10.7270/Q2WD4311
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 1 (Homo sapiens (Human))	BDBM50251722 (CHEMBL4098262) Show SMILES O=C1C=CC(=O)c2c1ccc1c3ccccc3oc(=O)c21 |c:2| Show InChI InChI=1S/C17H8O4/c18-12-7-8-13(19)15-11(12)6-5-10-9-3-1-2-4-14(9)21-17(20)16(10)15/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged CDC25A expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as s...				Eur J Med Chem 134: 316-333 (2017) Article DOI: 10.1016/j.ejmech.2017.04.012 BindingDB Entry DOI: 10.7270/Q2WD4311
					More data for this Ligand-Target Pair