BDBM50251748 2-(2,6-diethylphenyl)-4-methoxy-N-(2-methyl-5-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydroquinolin-5-amine::CHEMBL480156

SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)Nc1cc(ccc1C)C(F)(F)F

InChI Key: InChIKey=YATHWQCIZADVLH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50251748 (2-(2,6-diethylphenyl)-4-methoxy-N-(2-methyl-5-(tri...) Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)Nc1cc(ccc1C)C(F)(F)F Show InChI InChI=1S/C28H31F3N2O/c1-5-18-9-7-10-19(6-2)26(18)24-16-25(34-4)27-21(11-8-12-22(27)33-24)32-23-15-20(28(29,30)31)14-13-17(23)3/h7,9-10,13-16,21,32H,5-6,8,11-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 18: 3852-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.059 BindingDB Entry DOI: 10.7270/Q2765F4X
					More data for this Ligand-Target Pair