BDBM50251891 (4-(4-(3-(dimethylamino)propoxy)benzyl)piperazin-1-yl)(3,4-dichlorophenyl)methanone::CHEMBL519281

SMILES: CN(C)CCCOc1ccc(CN2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=RNNPMJNEXTUZEL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50251891 ((4-(4-(3-(dimethylamino)propoxy)benzyl)piperazin-1...) Show SMILES CN(C)CCCOc1ccc(CN2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C23H29Cl2N3O2/c1-26(2)10-3-15-30-20-7-4-18(5-8-20)17-27-11-13-28(14-12-27)23(29)19-6-9-21(24)22(25)16-19/h4-9,16H,3,10-15,17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair