BDBM50251918 ((R)-1-Cyclohexyl-ethyl)-{4-[2-methylsulfanyl-4-(3-trifluoromethyl-phenyl)-1H-imidazol-5-yl]-pyridin-2-yl}-amine::CHEMBL481942

SMILES: CSc1nc(c([nH]1)-c1cccc(c1)C(F)(F)F)-c1ccnc(N[C@H](C)C2CCCCC2)c1

InChI Key: InChIKey=MTTMKCUNIYFZNR-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50251918 (((R)-1-Cyclohexyl-ethyl)-{4-[2-methylsulfanyl-4-(3...) Show SMILES CSc1nc(c([nH]1)-c1cccc(c1)C(F)(F)F)-c1ccnc(N[C@H](C)C2CCCCC2)c1 |r| Show InChI InChI=1S/C24H27F3N4S/c1-15(16-7-4-3-5-8-16)29-20-14-18(11-12-28-20)22-21(30-23(31-22)32-2)17-9-6-10-19(13-17)24(25,26)27/h6,9-16H,3-5,7-8H2,1-2H3,(H,28,29)(H,30,31)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 51: 4122-49 (2008) Article DOI: 10.1021/jm701529q BindingDB Entry DOI: 10.7270/Q2W37X67
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