BDBM50251919 (1,2-Dimethyl-propyl)-{4-[2-methylsulfanyl-4-(3-trifluoromethyl-phenyl)-1H-imidazol-5-yl]-pyridin-2-yl}-amine::CHEMBL482111

SMILES: CSc1nc(c([nH]1)-c1cccc(c1)C(F)(F)F)-c1ccnc(NC(C)C(C)C)c1

InChI Key: InChIKey=AYBVIYITZRMSPJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50251919 ((1,2-Dimethyl-propyl)-{4-[2-methylsulfanyl-4-(3-tr...) Show SMILES CSc1nc(c([nH]1)-c1cccc(c1)C(F)(F)F)-c1ccnc(NC(C)C(C)C)c1 Show InChI InChI=1S/C21H23F3N4S/c1-12(2)13(3)26-17-11-15(8-9-25-17)19-18(27-20(28-19)29-4)14-6-5-7-16(10-14)21(22,23)24/h5-13H,1-4H3,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 51: 4122-49 (2008) Article DOI: 10.1021/jm701529q BindingDB Entry DOI: 10.7270/Q2W37X67
					More data for this Ligand-Target Pair