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BDBM50251927 (1,5-Dimethyl-hexyl)-{4-[4-(4-fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-yl}-amine::CHEMBL518964

SMILES: CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(C)CCCC(C)C)c1

InChI Key: InChIKey=HOKNJZWOUSWNLR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251927   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50251927
PNG
((1,5-Dimethyl-hexyl)-{4-[4-(4-fluoro-phenyl)-2-met...)
Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(C)CCCC(C)C)c1
Show InChI InChI=1S/C23H29FN4S/c1-15(2)6-5-7-16(3)26-20-14-18(12-13-25-20)22-21(27-23(28-22)29-4)17-8-10-19(24)11-9-17/h8-16H,5-7H2,1-4H3,(H,25,26)(H,27,28)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair