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SMILES: COCCn1c(SC)nc(c1-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1

InChI Key: InChIKey=OOKDYIKDKLFLOG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251939   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50251939
PNG
(CHEMBL481943 | Cyclohexyl-{4-[4-(4-fluoro-phenyl)-...)
Show SMILES COCCn1c(SC)nc(c1-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN4OS/c1-30-15-14-29-23(22(28-24(29)31-2)17-8-10-19(25)11-9-17)18-12-13-26-21(16-18)27-20-6-4-3-5-7-20/h8-13,16,20H,3-7,14-15H2,1-2H3,(H,26,27)
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Article
PubMed
n/an/a 42n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair