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SMILES: COCCn1c(SC)nc(c1-c1ccnc(NC2CCOCC2)c1)-c1ccc(F)cc1

InChI Key: InChIKey=VNBMSIFWXYVAOE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251941   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50251941
PNG
(CHEMBL481944 | {4-[4-(4-Fluoro-phenyl)-3-(2-methox...)
Show SMILES COCCn1c(SC)nc(c1-c1ccnc(NC2CCOCC2)c1)-c1ccc(F)cc1
Show InChI InChI=1S/C23H27FN4O2S/c1-29-14-11-28-22(21(27-23(28)31-2)16-3-5-18(24)6-4-16)17-7-10-25-20(15-17)26-19-8-12-30-13-9-19/h3-7,10,15,19H,8-9,11-14H2,1-2H3,(H,25,26)
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Similars
Article
PubMed
n/an/a 38n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair