BDBM50251950 (S)-4-(2,5-difluorophenyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2-phenyl-2H-pyrrole-1(5H)-carboxamide::CHEMBL481959

SMILES: CN(C1CCN(C)CC1)C(=O)N1CC(=C[C@H]1c1ccccc1)c1cc(F)ccc1F

InChI Key: InChIKey=ZQSDLUMGBYOLJF-QHCPKHFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50251950 ((S)-4-(2,5-difluorophenyl)-N-methyl-N-(1-methylpip...) Show SMILES CN(C1CCN(C)CC1)C(=O)N1CC(=C[C@H]1c1ccccc1)c1cc(F)ccc1F |r,c:14| Show InChI InChI=1S/C24H27F2N3O/c1-27-12-10-20(11-13-27)28(2)24(30)29-16-18(21-15-19(25)8-9-22(21)26)14-23(29)17-6-4-3-5-7-17/h3-9,14-15,20,23H,10-13,16H2,1-2H3/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEL cells				J Med Chem 51: 4239-52 (2008) Article DOI: 10.1021/jm800386y BindingDB Entry DOI: 10.7270/Q26D5SSB
					More data for this Ligand-Target Pair