BDBM50251971 CHEMBL481912::Cyclohexylmethyl-{4-[4-(4-fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-yl}-amine

SMILES: CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NCC2CCCCC2)c1

InChI Key: InChIKey=OMQTXNJFSQCJLQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50251971 (CHEMBL481912 | Cyclohexylmethyl-{4-[4-(4-fluoro-ph...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NCC2CCCCC2)c1 Show InChI InChI=1S/C22H25FN4S/c1-28-22-26-20(16-7-9-18(23)10-8-16)21(27-22)17-11-12-24-19(13-17)25-14-15-5-3-2-4-6-15/h7-13,15H,2-6,14H2,1H3,(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 51: 4122-49 (2008) Article DOI: 10.1021/jm701529q BindingDB Entry DOI: 10.7270/Q2W37X67
					More data for this Ligand-Target Pair