new BindingDB logo
myBDB logout

BDBM50251982 2-{4-[4-(4-Fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-ylamino}-butan-1-ol::CHEMBL480958

SMILES: CCC(CO)Nc1cc(ccn1)-c1nc(SC)[nH]c1-c1ccc(F)cc1

InChI Key: InChIKey=MVGCHYPFKGXJLN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251982   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50251982
PNG
(2-{4-[4-(4-Fluoro-phenyl)-2-methylsulfanyl-1H-imid...)
Show SMILES CCC(CO)Nc1cc(ccn1)-c1nc(SC)[nH]c1-c1ccc(F)cc1
Show InChI InChI=1S/C19H21FN4OS/c1-3-15(11-25)22-16-10-13(8-9-21-16)18-17(23-19(24-18)26-2)12-4-6-14(20)7-5-12/h4-10,15,25H,3,11H2,1-2H3,(H,21,22)(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair