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SMILES: COCCn1c(SC)nc(c1-c1ccnc(N[C@@H](C)c2ccccc2)c1)-c1ccc(F)cc1

InChI Key: InChIKey=WXFZPNQLVUNFGP-SFHVURJKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251990   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50251990
PNG
(CHEMBL516460 | {4-[4-(4-Fluoro-phenyl)-3-(2-methox...)
Show SMILES COCCn1c(SC)nc(c1-c1ccnc(N[C@@H](C)c2ccccc2)c1)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C26H27FN4OS/c1-18(19-7-5-4-6-8-19)29-23-17-21(13-14-28-23)25-24(20-9-11-22(27)12-10-20)30-26(33-3)31(25)15-16-32-2/h4-14,17-18H,15-16H2,1-3H3,(H,28,29)/t18-/m0/s1
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Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair