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BDBM50252041 (+/-)-N-(1-(4-(1-methylpyrrolidin-3-yloxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide::CHEMBL518949

SMILES: CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=ISEUXOPGKHVZKT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252041   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urotensin II receptor


(Homo sapiens (Human))
BDBM50252041
PNG
((+/-)-N-(1-(4-(1-methylpyrrolidin-3-yloxy)benzyl)p...)
Show SMILES CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C23H27Cl2N3O2/c1-27-10-9-20(15-27)30-19-5-2-16(3-6-19)13-28-11-8-18(14-28)26-23(29)17-4-7-21(24)22(25)12-17/h2-7,12,18,20H,8-11,13-15H2,1H3,(H,26,29)
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KEGG

UniProtKB/SwissProt

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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
97n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...


Bioorg Med Chem Lett 18: 3950-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.019
BindingDB Entry DOI: 10.7270/Q2FT8KTR
More data for this
Ligand-Target Pair