BDBM50252146 (S)-N-(1-(3-bromo-4-(2-(piperazin-1-yl)ethoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide::CHEMBL482258

SMILES: Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(OCCN3CCNCC3)c(Br)c2)C1

InChI Key: InChIKey=HBOMFIPWJMRXJO-IBGZPJMESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50252146 ((S)-N-(1-(3-bromo-4-(2-(piperazin-1-yl)ethoxy)benz...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(OCCN3CCNCC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C24H29BrCl2N4O2/c25-20-13-17(1-4-23(20)33-12-11-30-9-6-28-7-10-30)15-31-8-5-19(16-31)29-24(32)18-2-3-21(26)22(27)14-18/h1-4,13-14,19,28H,5-12,15-16H2,(H,29,32)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair