BDBM50252311 (+/-)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsulfonyl)azepan-3-yl)-3,4-dichlorobenzamide::CHEMBL521117

SMILES: Clc1ccc(cc1Cl)C(=O)NC1CCCCN(C1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1

InChI Key: InChIKey=ZYASYQCDNTWGJR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50252311 ((+/-)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsul...) Show SMILES Clc1ccc(cc1Cl)C(=O)NC1CCCCN(C1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1 Show InChI InChI=1S/C24H28BrCl2N3O4S/c25-20-14-19(5-7-23(20)34-18-8-10-28-11-9-18)35(32,33)30-12-2-1-3-17(15-30)29-24(31)16-4-6-21(26)22(27)13-16/h4-7,13-14,17-18,28H,1-3,8-12,15H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair