BDBM50252663 CHEMBL494879::{4-[4-(4-Fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-yl}-(1,2,3,4-tetra-hydronaphthalen-1-yl)-amine

SMILES: CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCc3ccccc23)c1

InChI Key: InChIKey=VRFQIBYIEAYTBZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50252663 (CHEMBL494879 | {4-[4-(4-Fluoro-phenyl)-2-methylsul...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCc3ccccc23)c1 Show InChI InChI=1S/C25H23FN4S/c1-31-25-29-23(17-9-11-19(26)12-10-17)24(30-25)18-13-14-27-22(15-18)28-21-8-4-6-16-5-2-3-7-20(16)21/h2-3,5,7,9-15,21H,4,6,8H2,1H3,(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 51: 4122-49 (2008) Article DOI: 10.1021/jm701529q BindingDB Entry DOI: 10.7270/Q2W37X67
					More data for this Ligand-Target Pair