BDBM50252814 1,1,1,3,3,3-Hexafluoro-2-{4-[methyl(phenylmethyl)amino]phenyl}-2-propanol::CHEMBL495494

SMILES: CN(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=WPDYLZPHLQWKCW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50252814 (1,1,1,3,3,3-Hexafluoro-2-{4-[methyl(phenylmethyl)a...) Show SMILES CN(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H15F6NO/c1-24(11-12-5-3-2-4-6-12)14-9-7-13(8-10-14)15(25,16(18,19)20)17(21,22)23/h2-10,25H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRalpha ligand binding domain				J Med Chem 51: 5758-65 (2008) Article DOI: 10.1021/jm800612u BindingDB Entry DOI: 10.7270/Q28052FN
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50252814 (1,1,1,3,3,3-Hexafluoro-2-{4-[methyl(phenylmethyl)a...) Show SMILES CN(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H15F6NO/c1-24(11-12-5-3-2-4-6-12)14-9-7-13(8-10-14)15(25,16(18,19)20)17(21,22)23/h2-10,25H,11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domain				J Med Chem 51: 5758-65 (2008) Article DOI: 10.1021/jm800612u BindingDB Entry DOI: 10.7270/Q28052FN
					More data for this Ligand-Target Pair