BDBM50252831 4-(p-Tolyl)spiro[chromene-2,4'-piperidine]::CHEMBL492448

SMILES: Cc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12

InChI Key: InChIKey=YDXKUUFNKUXOBE-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50252831 (4-(p-Tolyl)spiro[chromene-2,4'-piperidine] | CHEMB...) Show SMILES Cc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12 |t:8| Show InChI InChI=1S/C20H21NO/c1-15-6-8-16(9-7-15)18-14-20(10-12-21-13-11-20)22-19-5-3-2-4-17(18)19/h2-9,14,21H,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cells				J Med Chem 51: 5893-6 (2008) Article DOI: 10.1021/jm8008986 BindingDB Entry DOI: 10.7270/Q26W9C0D
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50252831 (4-(p-Tolyl)spiro[chromene-2,4'-piperidine] | CHEMB...) Show SMILES Cc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12 |t:8| Show InChI InChI=1S/C20H21NO/c1-15-6-8-16(9-7-15)18-14-20(10-12-21-13-11-20)22-19-5-3-2-4-17(18)19/h2-9,14,21H,10-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	462	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Inhibition of human ERG channel in HEK293 cells by voltage-clamp method				J Med Chem 51: 5893-6 (2008) Article DOI: 10.1021/jm8008986 BindingDB Entry DOI: 10.7270/Q26W9C0D
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50252831 (4-(p-Tolyl)spiro[chromene-2,4'-piperidine] | CHEMB...) Show SMILES Cc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12 |t:8| Show InChI InChI=1S/C20H21NO/c1-15-6-8-16(9-7-15)18-14-20(10-12-21-13-11-20)22-19-5-3-2-4-17(18)19/h2-9,14,21H,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS binding				J Med Chem 51: 5893-6 (2008) Article DOI: 10.1021/jm8008986 BindingDB Entry DOI: 10.7270/Q26W9C0D
					More data for this Ligand-Target Pair