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SMILES: CO\N=C(\C(=O)OC)c1ccccc1COc1cccc(OCc2ccc(Cl)cc2)c1

InChI Key: InChIKey=IZMPNVMWEYTSFQ-WNAAXNPUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253289   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))		BDBM50253289
PNG
(CHEMBL4090212)
Show SMILES CO\N=C(\C(=O)OC)c1ccccc1COc1cccc(OCc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C24H22ClNO5/c1-28-24(27)23(26-29-2)22-9-4-3-6-18(22)16-31-21-8-5-7-20(14-21)30-15-17-10-12-19(25)13-11-17/h3-14H,15-16H2,1-2H3/b26-23+
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n/an/a 600n/an/an/an/an/an/a



School of Chemistry and Biochemistry, Yeungnam University, 280 Daehak-Ro, Gyeongsan-si, Gyeongbuk 38541, Republic of Korea.

Curated by ChEMBL


Assay Description
Inhibition of hypoxia-induced HIF1alpha (unknown origin) transcriptional activity expressed in human HCT116 cells by HRE luciferase reporter gene ass...

Bioorg Med Chem Lett 27: 3026-3029 (2017)


Article DOI: 10.1016/j.bmcl.2017.05.024
BindingDB Entry DOI: 10.7270/Q2V69N15
More data for this
Ligand-Target Pair