BDBM50253460 CHEMBL493904::N2,N4-dimethyl-N2,N4-diisobutyl-6-[(2-naphthalen-1-yl-ethyl)-pyrimidin-2,4-yl]-diamine

SMILES: CC(C)CN(C)c1cc(CCc2cccc3ccccc23)nc(n1)N(C)CC(C)C

InChI Key: InChIKey=HDFUPFFBWIBIOT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50253460 (CHEMBL493904 | N2,N4-dimethyl-N2,N4-diisobutyl-6-[...) Show SMILES CC(C)CN(C)c1cc(CCc2cccc3ccccc23)nc(n1)N(C)CC(C)C Show InChI InChI=1S/C26H36N4/c1-19(2)17-29(5)25-16-23(27-26(28-25)30(6)18-20(3)4)15-14-22-12-9-11-21-10-7-8-13-24(21)22/h7-13,16,19-20H,14-15,17-18H2,1-6H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Binding affinity to ERalpha (unknown origin) assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 ...				J Med Chem 51: 6512-30 (2008) Article DOI: 10.1021/jm800698b BindingDB Entry DOI: 10.7270/Q2KD1XRF
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50253460 (CHEMBL493904 | N2,N4-dimethyl-N2,N4-diisobutyl-6-[...) Show SMILES CC(C)CN(C)c1cc(CCc2cccc3ccccc23)nc(n1)N(C)CC(C)C Show InChI InChI=1S/C26H36N4/c1-19(2)17-29(5)25-16-23(27-26(28-25)30(6)18-20(3)4)15-14-22-12-9-11-21-10-7-8-13-24(21)22/h7-13,16,19-20H,14-15,17-18H2,1-6H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Binding affinity to ERbeta (unknown origin) assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 b...				J Med Chem 51: 6512-30 (2008) Article DOI: 10.1021/jm800698b BindingDB Entry DOI: 10.7270/Q2KD1XRF
					More data for this Ligand-Target Pair