BDBM50253549 3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabicyclo[3.2.1]octan-3-ol::CHEMBL495129::endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo-[3.2.1]octan-3-ol

SMILES: OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1

InChI Key: InChIKey=AXPWNFAVTPIWHV-UHFFFAOYSA-N

Data: 10 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50253549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin)				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D4 receptor (unknown origin)				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [3H]8OH-DPAT from 5HT1A receptor (unknown origin)				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor (unknown origin)				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48.3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Antagonist activity at dopamine D2 receptor (unknown origin)				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50253549 (3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabi...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H23ClN2O/c23-17-7-5-16(6-8-17)22(26)11-18-9-10-19(12-22)25(18)14-15-13-24-21-4-2-1-3-20(15)21/h1-8,13,18-19,24,26H,9-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Antagonist activity at dopamine D3 receptor (unknown origin)				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair