BDBM50253552 CHEMBL494115::endo-8-(1H-Indol-3-ylmethyl)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
SMILES: OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(F)cc1
InChI Key: InChIKey=LEBXHMQTGORPIS-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50253552 (CHEMBL494115 | endo-8-(1H-Indol-3-ylmethyl)-3-(4-f...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuses Curated by ChEMBL | Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells | J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50253552 (CHEMBL494115 | endo-8-(1H-Indol-3-ylmethyl)-3-(4-f...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 41.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuses Curated by ChEMBL | Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells | J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q | |||||||||||
More data for this Ligand-Target Pair |