BDBM50253585 CHEMBL521648::endo-8-(5-Methoxy-1H-indol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol

SMILES: COc1ccc2[nH]cc(CN3C4CCC3CC(O)(C4)c3ccc(Cl)cc3)c2c1

InChI Key: InChIKey=HFZAKKDYDONOQJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50253585 (CHEMBL521648 | endo-8-(5-Methoxy-1H-indol-3-ylmeth...) Show SMILES COc1ccc2[nH]cc(CN3C4CCC3CC(O)(C4)c3ccc(Cl)cc3)c2c1 |TLB:9:10:12.13:18.16.15,19:16:12.13:10,THB:17:16:12.13:10| Show InChI InChI=1S/C23H25ClN2O2/c1-28-20-8-9-22-21(10-20)15(13-25-22)14-26-18-6-7-19(26)12-23(27,11-18)16-2-4-17(24)5-3-16/h2-5,8-10,13,18-19,25,27H,6-7,11-12,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50253585 (CHEMBL521648 | endo-8-(5-Methoxy-1H-indol-3-ylmeth...) Show SMILES COc1ccc2[nH]cc(CN3C4CCC3CC(O)(C4)c3ccc(Cl)cc3)c2c1 |TLB:9:10:12.13:18.16.15,19:16:12.13:10,THB:17:16:12.13:10| Show InChI InChI=1S/C23H25ClN2O2/c1-28-20-8-9-22-21(10-20)15(13-25-22)14-26-18-6-7-19(26)12-23(27,11-18)16-2-4-17(24)5-3-16/h2-5,8-10,13,18-19,25,27H,6-7,11-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair