BDBM50253587 1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxyprop-1-ynyl)-thiophen-2-yl]-1H-pyrazole-3-carboxylic Acid Piperidin-1-ylamide::CHEMBL523872

SMILES: Cc1c(nn(c1-c1ccc(s1)C#CCOc1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1

InChI Key: InChIKey=SYYJKQJOSWHETE-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50253587 (1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxypro...) Show SMILES Cc1c(nn(c1-c1ccc(s1)C#CCOc1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C29H26Cl2N4O2S/c1-20-27(29(36)33-34-16-6-3-7-17-34)32-35(25-14-12-21(30)19-24(25)31)28(20)26-15-13-23(38-26)11-8-18-37-22-9-4-2-5-10-22/h2,4-5,9-10,12-15,19H,3,6-7,16-18H2,1H3,(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells				J Med Chem 51: 5397-412 (2008) Article DOI: 10.1021/jm800066v BindingDB Entry DOI: 10.7270/Q24M94BM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50253587 (1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxypro...) Show SMILES Cc1c(nn(c1-c1ccc(s1)C#CCOc1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C29H26Cl2N4O2S/c1-20-27(29(36)33-34-16-6-3-7-17-34)32-35(25-14-12-21(30)19-24(25)31)28(20)26-15-13-23(38-26)11-8-18-37-22-9-4-2-5-10-22/h2,4-5,9-10,12-15,19H,3,6-7,16-18H2,1H3,(H,33,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18.7	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP binding				J Med Chem 51: 5397-412 (2008) Article DOI: 10.1021/jm800066v BindingDB Entry DOI: 10.7270/Q24M94BM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50253587 (1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxypro...) Show SMILES Cc1c(nn(c1-c1ccc(s1)C#CCOc1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C29H26Cl2N4O2S/c1-20-27(29(36)33-34-16-6-3-7-17-34)32-35(25-14-12-21(30)19-24(25)31)28(20)26-15-13-23(38-26)11-8-18-37-22-9-4-2-5-10-22/h2,4-5,9-10,12-15,19H,3,6-7,16-18H2,1H3,(H,33,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells				J Med Chem 51: 5397-412 (2008) Article DOI: 10.1021/jm800066v BindingDB Entry DOI: 10.7270/Q24M94BM
					More data for this Ligand-Target Pair