BDBM50253634 CHEMBL459496::endo-8-(Benzofur-3-ylmethyl)-3-(2,3-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol

SMILES: OC1(CC2CCC(C1)N2Cc1coc2ccccc12)c1cccc(Cl)c1Cl

InChI Key: InChIKey=GMEKBIQFYDAEOK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50253634 (CHEMBL459496 | endo-8-(Benzofur-3-ylmethyl)-3-(2,3...) Show SMILES OC1(CC2CCC(C1)N2Cc1coc2ccccc12)c1cccc(Cl)c1Cl |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H21Cl2NO2/c23-19-6-3-5-18(21(19)24)22(26)10-15-8-9-16(11-22)25(15)12-14-13-27-20-7-2-1-4-17(14)20/h1-7,13,15-16,26H,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50253634 (CHEMBL459496 | endo-8-(Benzofur-3-ylmethyl)-3-(2,3...) Show SMILES OC1(CC2CCC(C1)N2Cc1coc2ccccc12)c1cccc(Cl)c1Cl |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C22H21Cl2NO2/c23-19-6-3-5-18(21(19)24)22(26)10-15-8-9-16(11-22)25(15)12-14-13-27-20-7-2-1-4-17(14)20/h1-7,13,15-16,26H,8-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair