BDBM50254015 1-(2-(3,4-dichlorophenylthio)-2-(4-methoxyphenyl)ethyl)-1H-imidazole::CHEMBL459502::NSC-289311

SMILES: COc1ccc(cc1)C(Cn1ccnc1)Sc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=RUUOJGYNYNPAKU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50254015 (1-(2-(3,4-dichlorophenylthio)-2-(4-methoxyphenyl)e...) Show SMILES COc1ccc(cc1)C(Cn1ccnc1)Sc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H16Cl2N2OS/c1-23-14-4-2-13(3-5-14)18(11-22-9-8-21-12-22)24-15-6-7-16(19)17(20)10-15/h2-10,12,18H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPH				J Med Chem 52: 143-50 (2009) Article DOI: 10.1021/jm800945c BindingDB Entry DOI: 10.7270/Q2SQ9080
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50254015 (1-(2-(3,4-dichlorophenylthio)-2-(4-methoxyphenyl)e...) Show SMILES COc1ccc(cc1)C(Cn1ccnc1)Sc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H16Cl2N2OS/c1-23-14-4-2-13(3-5-14)18(11-22-9-8-21-12-22)24-15-6-7-16(19)17(20)10-15/h2-10,12,18H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPH				J Med Chem 52: 143-50 (2009) Article DOI: 10.1021/jm800945c BindingDB Entry DOI: 10.7270/Q2SQ9080
					More data for this Ligand-Target Pair