BDBM50254068 2-(2-chloro-4-(trifluoromethyl)phenylsulfonyl)-2-methyl-N-(quinolin-3-yl)propanamide::CHEMBL466185

SMILES: CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=CDMGPDPGOOJHDC-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50254068 (2-(2-chloro-4-(trifluoromethyl)phenylsulfonyl)-2-m...) Show SMILES CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C20H16ClF3N2O3S/c1-19(2,18(27)26-14-9-12-5-3-4-6-16(12)25-11-14)30(28,29)17-8-7-13(10-15(17)21)20(22,23)24/h3-11H,1-2H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in SF9 cells assessed as inhibition of CP55940-stimulated GTP binding				Bioorg Med Chem Lett 19: 31-5 (2008) Article DOI: 10.1016/j.bmcl.2008.11.026 BindingDB Entry DOI: 10.7270/Q2FF3S7X
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50254068 (2-(2-chloro-4-(trifluoromethyl)phenylsulfonyl)-2-m...) Show SMILES CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C20H16ClF3N2O3S/c1-19(2,18(27)26-14-9-12-5-3-4-6-16(12)25-11-14)30(28,29)17-8-7-13(10-15(17)21)20(22,23)24/h3-11H,1-2H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP55940-stimulated GTP binding				Bioorg Med Chem Lett 19: 31-5 (2008) Article DOI: 10.1016/j.bmcl.2008.11.026 BindingDB Entry DOI: 10.7270/Q2FF3S7X
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50254068 (2-(2-chloro-4-(trifluoromethyl)phenylsulfonyl)-2-m...) Show SMILES CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C20H16ClF3N2O3S/c1-19(2,18(27)26-14-9-12-5-3-4-6-16(12)25-11-14)30(28,29)17-8-7-13(10-15(17)21)20(22,23)24/h3-11H,1-2H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in CHO cells assessed as suppression of forskolin-stimulated cAMP accumulation				Bioorg Med Chem Lett 19: 31-5 (2008) Article DOI: 10.1016/j.bmcl.2008.11.026 BindingDB Entry DOI: 10.7270/Q2FF3S7X
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50254068 (2-(2-chloro-4-(trifluoromethyl)phenylsulfonyl)-2-m...) Show SMILES CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C20H16ClF3N2O3S/c1-19(2,18(27)26-14-9-12-5-3-4-6-16(12)25-11-14)30(28,29)17-8-7-13(10-15(17)21)20(22,23)24/h3-11H,1-2H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as suppression of forskolin-stimulated cAMP accumulation				Bioorg Med Chem Lett 19: 31-5 (2008) Article DOI: 10.1016/j.bmcl.2008.11.026 BindingDB Entry DOI: 10.7270/Q2FF3S7X
					More data for this Ligand-Target Pair