BDBM50254072 (R)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)butan-1-amine hydrochloride::CHEMBL512120
SMILES: CNCCC[C@@H](c1cccs1)c1cccc2[nH]ccc12
InChI Key: InChIKey=TYMPWFMJMZBIIE-OAHLLOKOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Transporter (Rattus norvegicus (rat)) | BDBM50254072 ((R)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 79.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50254072 ((R)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 271 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50254072 ((R)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 957 | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair |