BDBM50254086 CHEMBL4076700

SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)CN)[C@@H](C)CC)C(=O)NCC(N)=O

InChI Key: InChIKey=PGLBMFMLOXVEDR-WSDGLCEESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Atrial natriuretic peptide receptor (Homo sapiens (Human))	BDBM50254086 (CHEMBL4076700) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)CN)[C@@H](C)CC)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C45H81N17O12/c1-5-24(3)36(42(73)55-21-31(47)63)61-40(71)28(15-11-17-53-45(50)51)59-41(72)30(19-35(67)68)60-43(74)37(25(4)6-2)62-39(70)27(14-10-16-52-44(48)49)57-34(66)23-54-33(65)22-56-38(69)29(58-32(64)20-46)18-26-12-8-7-9-13-26/h24-30,36-37H,5-23,46H2,1-4H3,(H2,47,63)(H,54,65)(H,55,73)(H,56,69)(H,57,66)(H,58,64)(H,59,72)(H,60,74)(H,61,71)(H,62,70)(H,67,68)(H4,48,49,52)(H4,50,51,53)/t24-,25-,27-,28-,29-,30-,36-,37-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count method				Bioorg Med Chem Lett 27: 3542-3545 (2017) Article DOI: 10.1016/j.bmcl.2017.05.061 BindingDB Entry DOI: 10.7270/Q2F19241
					More data for this Ligand-Target Pair
Atrial natriuretic peptide receptor 3 (Homo sapiens (Human))	BDBM50254086 (CHEMBL4076700) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)CN)[C@@H](C)CC)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C45H81N17O12/c1-5-24(3)36(42(73)55-21-31(47)63)61-40(71)28(15-11-17-53-45(50)51)59-41(72)30(19-35(67)68)60-43(74)37(25(4)6-2)62-39(70)27(14-10-16-52-44(48)49)57-34(66)23-54-33(65)22-56-38(69)29(58-32(64)20-46)18-26-12-8-7-9-13-26/h24-30,36-37H,5-23,46H2,1-4H3,(H2,47,63)(H,54,65)(H,55,73)(H,56,69)(H,57,66)(H,58,64)(H,59,72)(H,60,74)(H,61,71)(H,62,70)(H,67,68)(H4,48,49,52)(H4,50,51,53)/t24-,25-,27-,28-,29-,30-,36-,37-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-human ANP from His-tagged and Fc fragment containing human NPR-3 extracellular domain expressed in FreeStyle 293 cells incubat...				Bioorg Med Chem Lett 27: 3542-3545 (2017) Article DOI: 10.1016/j.bmcl.2017.05.061 BindingDB Entry DOI: 10.7270/Q2F19241
					More data for this Ligand-Target Pair