BDBM50254126 CHEMBL468275::N-(4-chloro-2-(trifluoromethoxy)phenyl)-2-(4-chlorophenylsulfonyl)-2-methylpropanamide

SMILES: CC(C)(C(=O)Nc1ccc(Cl)cc1OC(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=RFZLSIBCGIWYTG-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50254126 (CHEMBL468275 | N-(4-chloro-2-(trifluoromethoxy)phe...) Show SMILES CC(C)(C(=O)Nc1ccc(Cl)cc1OC(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14Cl2F3NO4S/c1-16(2,28(25,26)12-6-3-10(18)4-7-12)15(24)23-13-8-5-11(19)9-14(13)27-17(20,21)22/h3-9H,1-2H3,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP55940-stimulated GTP binding				Bioorg Med Chem Lett 19: 31-5 (2008) Article DOI: 10.1016/j.bmcl.2008.11.026 BindingDB Entry DOI: 10.7270/Q2FF3S7X
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50254126 (CHEMBL468275 | N-(4-chloro-2-(trifluoromethoxy)phe...) Show SMILES CC(C)(C(=O)Nc1ccc(Cl)cc1OC(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14Cl2F3NO4S/c1-16(2,28(25,26)12-6-3-10(18)4-7-12)15(24)23-13-8-5-11(19)9-14(13)27-17(20,21)22/h3-9H,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in SF9 cells assessed as inhibition of CP55940-stimulated GTP binding				Bioorg Med Chem Lett 19: 31-5 (2008) Article DOI: 10.1016/j.bmcl.2008.11.026 BindingDB Entry DOI: 10.7270/Q2FF3S7X
					More data for this Ligand-Target Pair