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SMILES: O=C(Nc1ccc(cc1)S(=O)(=O)c1ccccc1)N1Cc2ccccc2C1

InChI Key: InChIKey=DFFUKTYAAFJSJU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50254213   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50254213
PNG
(CHEMBL4076641)
Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C21H18N2O3S/c24-21(23-14-16-6-4-5-7-17(16)15-23)22-18-10-12-20(13-11-18)27(25,26)19-8-2-1-3-9-19/h1-13H,14-15H2,(H,22,24)
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PubMed
 21n/an/an/an/an/an/an/an/a



AbbVie Inc, 1 North Waukegan Rd., North Chicago, IL 60064, United States. Electronic address: mike.curtin@abbvie.com.

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...

Bioorg Med Chem Lett 27: 3317-3325 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.018
BindingDB Entry DOI: 10.7270/Q2D22123
More data for this
Ligand-Target Pair