BDBM50254395 1-(4-chlorophenyl)-1-methyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)urea::CHEMBL468910

SMILES: CN(C(=O)Nc1cc(oc1C)S(=O)(=O)N1CCCCC1)c1ccc(Cl)cc1

InChI Key: InChIKey=MKFYBFAZPIICFT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50254395 (1-(4-chlorophenyl)-1-methyl-3-(2-methyl-5-(piperid...) Show SMILES CN(C(=O)Nc1cc(oc1C)S(=O)(=O)N1CCCCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H22ClN3O4S/c1-13-16(20-18(23)21(2)15-8-6-14(19)7-9-15)12-17(26-13)27(24,25)22-10-4-3-5-11-22/h6-9,12H,3-5,10-11H2,1-2H3,(H,20,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254395 (1-(4-chlorophenyl)-1-methyl-3-(2-methyl-5-(piperid...) Show SMILES CN(C(=O)Nc1cc(oc1C)S(=O)(=O)N1CCCCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H22ClN3O4S/c1-13-16(20-18(23)21(2)15-8-6-14(19)7-9-15)12-17(26-13)27(24,25)22-10-4-3-5-11-22/h6-9,12H,3-5,10-11H2,1-2H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair