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BDBM50254396 1-methyl-1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-3-phenylurea::CHEMBL512119

SMILES: CN(C(=O)Nc1ccccc1)c1cc(oc1C)S(=O)(=O)N1CCCCC1

InChI Key: InChIKey=DQLXFTXMXKHOFK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254396   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM50254396
PNG
(1-methyl-1-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Show SMILES CN(C(=O)Nc1ccccc1)c1cc(oc1C)S(=O)(=O)N1CCCCC1
Show InChI InChI=1S/C18H23N3O4S/c1-14-16(20(2)18(22)19-15-9-5-3-6-10-15)13-17(25-14)26(23,24)21-11-7-4-8-12-21/h3,5-6,9-10,13H,4,7-8,11-12H2,1-2H3,(H,19,22)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of endothelial lipase (unknown origin)


Bioorg Med Chem Lett 19: 27-30 (2008)

More data for this
Ligand-Target Pair
Lipoprotein lipase


(Rattus norvegicus)
BDBM50254396
PNG
(1-methyl-1-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Show SMILES CN(C(=O)Nc1ccccc1)c1cc(oc1C)S(=O)(=O)N1CCCCC1
Show InChI InChI=1S/C18H23N3O4S/c1-14-16(20(2)18(22)19-15-9-5-3-6-10-15)13-17(25-14)26(23,24)21-11-7-4-8-12-21/h3,5-6,9-10,13H,4,7-8,11-12H2,1-2H3,(H,19,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of Lipoprotein lipase from adipose tissue of rat


Bioorg Med Chem Lett 19: 27-30 (2008)

More data for this
Ligand-Target Pair