BDBM50254432 1-(2-methyl-5-(morpholinosulfonyl)furan-3-yl)-3-phenylurea::CHEMBL513697

SMILES: Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)N1CCOCC1

InChI Key: InChIKey=CGHGOYBTSNAPFZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50254432 (1-(2-methyl-5-(morpholinosulfonyl)furan-3-yl)-3-ph...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H19N3O5S/c1-12-14(18-16(20)17-13-5-3-2-4-6-13)11-15(24-12)25(21,22)19-7-9-23-10-8-19/h2-6,11H,7-10H2,1H3,(H2,17,18,20)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254432 (1-(2-methyl-5-(morpholinosulfonyl)furan-3-yl)-3-ph...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H19N3O5S/c1-12-14(18-16(20)17-13-5-3-2-4-6-13)11-15(24-12)25(21,22)19-7-9-23-10-8-19/h2-6,11H,7-10H2,1H3,(H2,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair