BDBM50254434 5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid (2-methoxy-ethyl)-methyl-amide::CHEMBL468281
SMILES: COCCN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1
InChI Key: InChIKey=XESWBZAIRXTAPJ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelial lipase (Homo sapiens (Human)) | BDBM50254434 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of endothelial lipase (unknown origin) | Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoprotein lipase (Rattus norvegicus) | BDBM50254434 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat | Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ | |||||||||||
More data for this Ligand-Target Pair |