BDBM50254730 2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(phenylsulfonyl)acetamide::CHEMBL464063

SMILES: O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1ccccc1

InChI Key: InChIKey=SOIJIWKNCRTWIB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50254730 (2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(ph...) Show SMILES O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H20N2O4S2/c29-25(28-34(30,31)21-9-2-1-3-10-21)17-32-23-12-6-11-22-26(23)24(16-27-22)33-20-14-13-18-7-4-5-8-19(18)15-20/h1-16,27H,17H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50254730 (2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(ph...) Show SMILES O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H20N2O4S2/c29-25(28-34(30,31)21-9-2-1-3-10-21)17-32-23-12-6-11-22-26(23)24(16-27-22)33-20-14-13-18-7-4-5-8-19(18)15-20/h1-16,27H,17H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.1	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair