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BDBM50254766 2-(3-(2,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide::CHEMBL465122

SMILES: Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)cc3Cl)c12

InChI Key: InChIKey=KELDWJSEGVJUPN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50254766
PNG
(2-(3-(2,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)cc3Cl)c12
Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-10-4-5-15(11(22)6-10)31-16-8-25-13-2-1-3-14(19(13)16)30-9-17(27)26-33(28,29)18-7-12(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 27.6n/an/an/an/an/an/a



deCODE Chemistry, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP3 receptor


Bioorg Med Chem Lett 19: 123-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.007
BindingDB Entry DOI: 10.7270/Q2JH3M1S
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50254766
PNG
(2-(3-(2,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)cc3Cl)c12
Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-10-4-5-15(11(22)6-10)31-16-8-25-13-2-1-3-14(19(13)16)30-9-17(27)26-33(28,29)18-7-12(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.200n/an/an/an/an/an/a



deCODE Chemistry, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum


Bioorg Med Chem Lett 19: 123-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.007
BindingDB Entry DOI: 10.7270/Q2JH3M1S
More data for this
Ligand-Target Pair